|Mifepristone and Misoprostol
|Zydus Lifesciences Limited
How It Works
Mifepristone, which is part of the MTP Kit, functions by preventing progesterone’s ability to cause the placenta to separate from the endometrium. Misoprostol facilitates the easy passage of the uterine contents by softening the cervix and increasing uterine contractions. When the bleeding begins, the uterine contents are typically blood clots that are passed through the vagina.
One tablet of mifepristone and four tablets of misoprostol make up the MTP Kit. It is recommended to take mifepristone orally, along with water. It is advised to take the four Misoprostol tablets 24 to 48 hours after taking the Mifepristone tablet.
Misoprostol can be administered vaginally or buccally. The four tablets must be put into the cheek pouch in order to be administered buccal. Put the two Misoprostol pills on one side of your mouth and the remaining pills on the other (in your cheek pouch, behind your teeth). The remaining contents should be ingested with water after 25 to 30 minutes. Usually, bleeding begins in the first four hours. It’s advisable to have some sanitary pads on hand because the bleeding will be more intense than usual.
The four tablets should be inserted into the vagina one at a time for vaginal administration. The pills must be reinserted if they fall out before the bleeding begins.
It is advised to follow up with the doctor’s office two weeks following the abortion.
Missed Dosage: Take this medication as directed by your physician. As a result, there is no chance of missing a dose.
Overdose: This medication is typically taken under a doctor’s supervision. If, on the other hand, your doctor tells you to take the pills at home and you suspect an overdose, call him or her right away.
Before using MTP Kit, let your physician know:
- If you have an allergy to any other drugs or metronidazole.
- If you suffer from a bleeding illness.
- If you suffer from a liver or kidney condition.
- If you experience diabetes, high blood pressure, etc.
- If your blood pressure is out of control.
- If you’ve previously experienced a heart attack, stroke, etc.
- If your anemia is very severe.
- If you have any inherited skin disease.
The following are typical MTP Kit side effects:
- Chills or hot flushes
- Pelvic pain
- Heavy menstrual bleeding
See your doctor right away if you soak two or more sanitary pads in less than two hours or if you suffer any long-term side effects.
It is well known that some medications can interact with MTP Kit and change how it functions. Inform your doctor about any herbal, over-the-counter, recreational, or other medications you take.
- Antibiotics such as erythromycin
- Antifungals such as ketoconazole
- Corticosteroids such as dexamethasone
- HIV Protease inhibitors such as indinavir and ritonavir
Interaction with alcohol
Drinking alcohol may make adverse effects more likely. Don’t drink alcohol while taking this medication.
The MTP Kit needs to be kept in its original packaging for safe and appropriate storage.
- The medication should not be exposed to direct sunlight, moisture, or heat.
- Keep the medication out of children’s reach.
- The remaining pills should be kept in an airtight container after the pack is opened.
- The medication should not be used after its expiration date.
Frequently Asked Questions (FAQs)
Is using the MTP Kit safe?
The MTP Kit is a medication-assisted birth control method that is both safe and effective for ending a woman’s pregnancy. It can end an intrauterine pregnancy with up to 63 days of gestation, according to clinical evidence.
How effective is the MTP Kit?
With an efficacy rate of up to 98.8% when taken during the first 6 weeks (or 42 days) of pregnancy and 95.5% when taken between weeks 7 and 9, the MTP Kit is regarded as an effective method of abortion. This kit can be used by women to end their pregnancy in the first trimester.
What is the duration of the MTP Kit’s operation?
Indeed. Pregnancy tissue typically passes out during the first four to six hours of life. After the pregnancy tissue is expelled, cramping and bleeding become less severe. After two weeks, a follow-up visit with the doctor might be advised.
When should you stop taking these medications?
Although the abortion pill is a safe way to end a pregnancy during the first nine weeks, it’s not always the best choice. Consequently, if you have any of the following, an MTP Kit might not be the best option for you:
- An ectopic pregnancy is one that is implanted outside of the uterus and requires medical attention only.
- Persistent failure of the liver or adrenals.
- Have HIV: If you have HIV, getting an abortion may increase your risk of contracting the virus. As a result, you should speak with your doctor before using the abortion pill and take antibiotics at the same time.
- A sexually transmitted infection (STI): you should see a doctor for treatment if you have gonorrhea or another similar infection.
- If you have an IUD in place, you should get it taken out before taking the abortion pill.
- Have porphyria: Porphyria is a hereditary disease that impairs the blood’s capacity to supply oxygen to tissues and organs.
How can an abortion be verified?
It is advised to schedule a follow-up appointment to confirm that the abortion is finished. Your physician might advise you to go to the clinic so that a physician can do an ultrasound, blood test, or brief examination.
What are the vital safety measures you need to take following an abortion?
After the abortion, try to schedule a day or two of rest. Following the abortion, the following safety measures need to be taken:
- The first week should be spent away from intense exercise.
- For two to three weeks, refrain from putting anything—including sex toys and tampons—into the vagina.
- Steer clear of stimulating the nipples in order to lessen discharge.
Most symptoms usually disappear within a day.
Are there any potential issues that I should be aware of?
Symptoms of potential issues include:
- Fever exceeding 101°F that lasts longer than 24 hours.
- Severe continuous bleeding, soaking two or more pads in an hour for two consecutive hours.
- Vomiting, diarrhea, or nausea that doesn’t go away after 24 hours.
- Unpleasant-smelling vaginal secretions.
- Severe cramping or pain that is not relieved by medicine.
- Pregnancy symptoms that persist after two to four weeks.
See your doctor right away if you encounter any of these symptoms. These symptoms might suggest that more care is needed.
Does the Abortion Pill differ in any way from Medical Abortion?
The pill for abortion is marketed under several names. On the other hand, the abortion pill is the same as medical, medication, and medicated abortions.